| The number of people suffering from obesity is steadily increasing
together with the risk of heart diseases, diabetes and some forms of cancer. Modern
methods of treatment for obesity have a significant problem - the body quickly
regains its original weight after the patient finishes the treatment.
This is because patients are unable to give up their habits when it comes to
their favorite food and have difficulties following complex therapies based on
a strict diet. The Standard Medislim Program for weight reduction enables quick
and effective weight loss without strict restrictions of food intake.
Materials and methods
We performed a preliminary statistic analysis of 52 case histories of somatic
healthy women during the first three months of their standard 6-month Medislim
program.
We studied the dynamic characteristics of weight, blood sugar, cholesterol,
triglyceride, SGOT and SGPT with relation to body mass index (BMI).
The results of the research
In our study 16 women (30.76%) had excess body weight (with BMI under 28), 36
women (69.2%) suffered from obesity (with BMI over 28). In 7.6% of the cases,
the BMI level exceeded 46.5. We separated women into two groups: Group A, with
19 women (36.54%) suffering from obesity and having normal biochemical characteristics;
Group B, with 33 women (36.46%) having abnormal biochemical characteristics. Both
groups were further separated into two subgroups based on their BMI levels. The
first subgroup had BMI levels under 28. The second subgroup had BMI levels over
28. We presented the data in Tables 3 and Table 4.
Table 1: Body mass index of the group A and B.
| Group |
No. |
Height |
sq.m/kg |
Body mass % reduce
|
Weight |
| 1 |
2 |
| A |
1 |
7(13.46%) |
165.5 |
25.94 |
67.2 |
61.4 |
8.38 |
| 2 |
12(23%) |
160.8 |
33.3 |
86.12 |
76.8 |
110.83 |
| B |
1 |
9 (17.3%) |
157.4 |
25.1 |
61.8 |
55.82 |
9.7 |
| 2 |
24(46.15%) |
159.53 |
33.6 |
84.45 |
77.46 |
9.34 |
Table 2: Biochemical indexes of group B.
| Group |
N |
CH (n) |
TR (m) |
SGOT (unit) |
SGPT (unit) |
| 1 |
2 |
1 |
2 |
1 |
2 |
1 |
2 |
| B |
1 |
9 |
287.5 |
252.88 |
345 |
252 |
55.25 |
41 |
84 |
57 |
| 2 |
24 |
280 |
236.75 |
274.3 |
226 |
52 |
42.16 |
54.36 |
43.36 |
Discussion on the results
The obtained data indicates a real weight loss for women of all groups (p<0.001)
as the result of the treatment. The weight loss percentage during first 3 months
was 9.56%, which is equal to 7.56kg. Women with BMI levels of 25-28 obtained a
weight loss of 9.4% (5.89 kg), those with BMI higher than 28 obtained a weight
loss of 10.1% (8.65kg). The biggest weight loss was among women of Subgroup A2
(with BMI levels over 28, having normal biochemical characteristics). The women
from this Subgroup lost 9.32kg (10.83%). The least weight loss occurred in women
from Subgroup B-1 (women with BMI less than 28 and with abnormal biochemical characteristics).
Those women lost 5.98kg (9.7%).
Before treatment, laboratory tests from the women of Group A were statistically
normal. 58.6% of women from Group B had a real increase of cholesterol levels
compared to group A, at 283.7n (p<0.001) and 41% of the women had an increase
of triglyceride levels, at 309.6m (p<0.001).
The SGOT and SGPT levels were higher than normal in 34.48% of cases - at 53.62u
(p<0.001) and 69.18u (p<0.001) respectively.
After comparing the results in Subgroups 1 and 2 of Group B, we did not reveal
whether BMI levels were dependent on biochemical factors before and after the
treatment.
As a result of the treatment, cholesterol decreased to normal levels for women
from Subgroup B2 (47%). All other patients of group B showed a tendency to bring
their biochemical characteristics to a normal range.
The blood sugar levels of all patients were within normal range before and
after the treatment.
Conclusion
The analysis of the results of the Medislim treatment shows us a high effectiveness
of the treatment for overweight and obese women. In 47% of the cases, quicker
weight loss went together with the normalization of cholesterol levels. The degree
of the weight loss depended on the obesity level and liver function. Medislim
was shown to have no negative effects on liver function, and this allows us to
use Medislim to treat overweight patients with liver dysfunction.
Dr. Anchulee Yongarnukul and staff
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